Persistent random walk model of cell migration over curved substrate
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- Cell migration
- Curvature
- Numerical model
- Cell migration Curvature numerical model
- Cell migration
Cell migration is a key process in tissue formation which occurs during embryo's development or regeneration. Among the numerous factors in the cell environment that impact cell behavior, substrate cell-scale curvature is a mechanical cue which redirects cells toward concave areas. However, the process of change in directionality remains unknown: it may emerge from the activation of signal pathways by the curvature and/or the cell would be mechanically limited by the curvature.
Institut des Sciences du Mouvement Etienne-Jules Marey | Aix Marseille Université - Tous droits réservés - Mentions légales