In occupational situations, accidents referred to as accidents on the level (AoLs) occur most of the time when locomotion control fails. This control is determined by the interactions between the operator and the environment, the task and the used tools. Hence, AoLs prevention requires developing ways to optimise these interactions. More fundamentally, AoLs prevention requires understanding locomotion control in situations where this control is at sake, that is in situations involving one or more AoLs factors. The purpose of this article is to propose a comprehensive model for the control of locomotion in occupational environments. This model featuring the operator, the task and the working space should be an appropriate tool to understand AoLs in the scope of their prevention. Firstly, we describe what occupational AoLs are. In a second part, we present a review of the theoretical and experimental knowledge related to the locomotion system through the various means developed by the Central Nervous System to cope with perturbations of the environment and/or particular constraints from the task. Finally, we propose a simplified systemic model presenting the various levels of control (sensory-motor to cognitive levels) describing locomotion in occupational situations, and we suggest experiments likely to produce the appropriate data to construct the final comprehensive model.