Fatigue, decrease of physical capacity, decrease of quality of life ... are direct consequences of cancer and related treatments. Contend against the decline of patients’ quality of life is now a priority in the fight against cancer ( “Plan Cancer 2014-2019”). Adapted physical activity has proven effective for patients undergoing cancer treatment. This thesis, described as "action-research", was conducted at the Institut of Movement Sciences (CNRS UMR 7287 AMU). As part of collaboration with the Institut Paoli Calmettes, Centre de Lutte Contre le Cancer in the PACA region, the objective of this work was to contribute to knowledge development in the field of adapted physical activity in oncology. This research’s program was organized in 5 studies, collecting 262 subjects. Firstly, the main results illustrated that adapted physical activity is beneficial for very specific populations (Study 1); secondly we demonstrated that physical activity remotely managed via new technologies could be a real alternative to supervised programs (Study 3). Furthermore, an additional study (Study 2) revealed a very limited involvement of patients in these programs. For the first time in literature, we revealed that the time perspective is a variable to be considered in the promotion of physical activity for patients (Study 4) as well as personality, age and type of hospital (Study 5). This thesis sheds new light both in terms of the contribution of scientific knowledge and on therapeutic proposals in order to develop and improve supportive physical activity for patients suffering from cancer.