Availability of Morphine Oral Solution for Childhood Cancer Patients in Low-Income Countries: Compounding and Stability Study in a Cote d'Ivoire University Teaching Hospital

  • Pourroy Bertrand
  • Curti Christophe
  • Lamy Edouard
  • N'Gbesso Jauhel
  • Krasse Innocent
  • Vanelle Patrice


The purpose of our study was to develop an affordable and easily available oral morphine formulation for pediatric patients with cancer pain.We devised an easy-to-make and low-cost morphine syrup formulation using local African (Cote d’Ivoire) raw materials and commercial injectable morphine. In this report, we describe the results of a study to assess the required quality controls and stability of this formulation.