AMISIA a multidisciplinary, 36 months Defi CNRS AUTON project, aimed at the secondary prevention of the loss of autonomy for patients with traumatic brain injury and stroke. As “any patient is a unique case,” AMISIA proposes an integrated approach, mixing medical health devices, information technology, and human factors to provide patients, health care actors and caregivers from the relatives both the best incentives and high degree of monitoring. This first step aims to define a methodology to determine the indicators necessary to promote physical activity in traumatic brain injury and stroke patient. In line with the primary aim, we conducted a data collection experiment in Limoges with 61 volunteer participants. Data were biographic elements, socio - econo mic profiles, cognitive performance (Corsi test results), psychological battery (anxiety, fatigue, sleep), posture and gait measurement with 4 Imus and a Wii - balance board, and finally the physical activity over a week at home (Armband and Fitbit sensors). These data will help build a control database, to help extract individual profiles with machine learning techniques. Index Terms -Secondary prevention, stroke , brain traumatic injury , activity incentive, multidimensional data collection